Pharmacosmos obtains first marketing authorisations for Monofer®

January 26, 2010

Pharmacosmos today announced that it has obtained marketing authorisations for Monofer® in Denmark, Iceland and the Netherlands. As Pharmacosmos' first marketing authorisations for Monofer®, the decisions pave the way for the first wave of Monofer® launches in the second quarter of 2010.

Monofer® (iron isomaltoside 1000) is a new treatment for iron deficiency anaemia developed by Pharmacosmos. The only IV iron preparation that offers both the widest accepted dose range and no test dose requirement1, Monofer® has the potential to help millions of patients each year.

The marketing authorisations in Denmark, Iceland and the Netherlands enable Pharmacosmos to prepare to launch the product in the first wave of countries in 2010. The decisions follow a positive outcome for the registration of Monofer® in a decentralised procedure in 22 European countries on 26 November 2009 - and Pharmacosmos expects to obtain marketing authorisations in the remaining countries during 2010.

Lars Christensen, M.D., President and CEO of Pharmacosmos, comments: "We are delighted to have received the first marketing authorisation for Monofer®, especially as the decision fits with our anticipated timeline for launch. Iron deficiency anaemia is a global health problem. Patients suffering from it need fast iron repletion in one treatment. That's what Monofer® offers - and we believe it will be a very important product in the treatment field."

Pharmacosmos is currently collaborating with its international partners to prepare launch activities - and will be ready for the first wave of launches later in the year.

As part of its ongoing clinical programme, Pharmacosmos initiated a new international gastroenterological study2 in the treatment of iron deficiency anaemia in patients with inflammatory bowel disease (IBD) in October 2009. The ongoing clinical programme aims to expand the clinical documentation of the safety and efficacy of Monofer® as a treatment for iron deficiency anaemia within nephrology, oncology and gastroenterology.

The efficacy and safety of Monofer® have already been documented in clinical studies in patients with chronic kidney disease (CKD) and congestive heart failure (CHF).


Further information

Learn more and sign-up for the latest updates about Monofer® at Monofer.com or contact:

Lars Christensen, M.D.
President and CEO
T: +45 59 48 59 59
E: monofer@pharmacosmos.com


References

1) Core SPC, 2) ClinicalTrials.gov identifier no. NCT01017614

© 2010 Pharmacosmos A/S. Monofer® is a registered trademark of Pharmacosmos A/S.

About Pharmacosmos A/S

Pharmacosmos develops and markets medicines for the treatment of iron deficiency. A research-based company, its ongoing R&D programme focuses on improving the treatment options for healthcare professionals and patients suffering from iron deficiency.

Pharmacosmos is a privately-owned Danish company and operates in more than 50 countries across Europe, the Americas and Asia. Its facilities are approved by the Danish Medicines Agency and the US Food & Drug Administration.